老年乳腺癌的临床特点及预后因素

The clinical characteristics and prognosis factors for the old patients with breast cancer

目的:探讨老年乳腺癌的临床特点及影响其预后的相关因素。方法:从我院1979年1月至1998年12月20年间收治的819例女性乳腺癌患者中,收集整理≥60岁的女性乳腺癌176例,对其进行分析。结果:本组176例老年乳腺癌患者平均年龄67.6岁,其中60岁～70岁占82.9％。平均病程是19.94月。TNM分期Ⅲ、Ⅳ期43例（24.43）％,伴有合并症者87例（49.43％）,腋下淋巴结有转移者80例（45.45％）,5年生存率65.34％。结论:①病程长,但病期相对并不晚。②老年乳腺癌发展慢。③老年乳腺癌病人多伴有合并症。④其预后与患者的合并症,组织学恶性程度,雌激素水平等有关,给予适当合理的治疗能明显改善其预后。

Objective: To analyse the clinical characteristics and the factors influencing prognosis of breast cancer in the old. Methods: The results of treatment in cases of breast cancer in the old (From 1979 to 1998 in our department) were reviewed.Results:①The mean age of the 176 patients is 67.6 years old and their mean course is 19.94 months.②The number of TNM stage Ⅲ and stage Ⅳ is 43 cases (24.43 % ), 5 years survival rate is 65.34 % . Conclusions; The clinical characteristics of breast cancer in the old are as following:①Long course but not always late TNM stage. ②better prognosis. ③always with complications. Having complications, histocharacteristics and the hormore receptor status are important factors influencing prognosis of breast cancer in the old. The perfect treatment can obviously improve their prognosis.