巨细胞病毒感染在抽动障碍中的临床意义初探

Human Cytomegalovirus Infection in Children with Tic Disorders

目的 :探讨人巨细胞病毒 (humancytomegalovirus ,HCMV)感染在抽动障碍中的临床意义。方法 :应用PCR基因扩增技术对 6 6例抽动障碍患儿进行血液HCMV检测 ,并测定 74例正常儿童作为对照。结果 :抽动障碍患儿HCMV检出阳性率 (2 6 % )明显高于对照组 (3 % ) ,差异有显著性 (p <0 0 1) ,抽动障碍三种类型间HCMV感染阳性率无显著性差异 (p >0 0 5 )。结论

Objective: To explore the situation of human cytomegalovirus (HCMV) infection in children with tic disorders Method: The HCMV were determined in blood sample taken from 66 cases of tic disorders by polymerase chain reaction (PCR), while 74 normal children were tested either as control Results: The positive rate in tic group (26%) was significantly higher than that of control (3%, p<0 01) There was no difference of this rate among the 3 subtypes of tic disorders Conclusion: HCMV infection is more common in children with tic disorders and has no difference among the three subtypes