精神分裂症患者近期结局的影响因素及干预对策

Factors influencing the short-term outcome and intervention measures of patients with the first episode of schizophrenia

目的 :分析首次发病精神分裂症患者近期结局的影响因素 ,为制定有效的干预对策提供理论依据。方法 :以一系列标准化评定工具 ,对符合 CCMD- 2 - R诊断标准的 16 0例首发精神分裂症患者进行为期 2年的随访评估 ,对所得资料进行单因素分析和多元逐步回归分析。结果 :首发精神分裂症 2年随访时结局良好者达 5 9.9% ,影响其近期结局的主要因素为 :随访期服药治疗情况、社会支持、思维贫乏、注意障碍、病前职业功能水平、意志缺乏。结论 :首发精神分裂症患者近期结局较好 ,受生物、心理、社会等多方面因素的影响 ,在一定程度上可以人为干预 ,并提出了干预对策。

Objective:To analyze the factors influencing the short-term outcome of first episode schizophrenic patients and give recouineudetions theoretical accordance for making these interventions .Method 160 cases of first episode schizophrenia patients were assessed using standard assessment instruments. The information was analyzed by means of multivariate analyses of stepwise regression. Results:59.9% of first episode schizophrenia patients had a good global outcome at the end of a two year follow-up. The main influential factors were maintenance treatment during follow-up,social support,poverty of thougyt ,attention disturbance,premorbid level of occupational function and abulia. Conclusion:The findings suggest that outcome of the first episode schizophrenia patients was genecally good.Some factors play an important role in the quality of outcome . At last corresponding intervention measures.