带状疱疹病人外周血T细胞亚群及IL-2的检测

T-LYMPHOCYTE SUBGROUP AND IL-2 IN PERIPHERAL BLOOD IN PATIENTS WITH HERPES ZOSTER

①目的 探讨T淋巴细胞亚群及白细胞介素 2 (IL 2 )水平对带状疱疹发病的影响。②方法 用碱性磷酸酶抗碱性磷酸酶法 (APAAP)检测 30例带状疱疹病人、30例正常人外周血CD+ 4,CD+ 8,用双抗体夹心ELISA法检测血清IL 2水平。③结果 带状疱疹病人血清CD+ 8明显增高 ,而CD+ 4,IL 2 ,CD+ 4/CD+ 8明显降低 ,与对照组比较差异有显著性 (t=2 .89～ 5 .6 4,P <0 .0 1)。④结论 T淋巴细胞亚群及血清IL

Objective\ To explore the effect of T lymphocyte subgroup and IL 2 in the pathogenesis of herpes zoster. Methods\ Alkaline phosphatase anti alkaline phosphatase (APAAP)method was used to determine the levels of CD + 4 and CD + 8 T lymphocyte, and double antibody sandwich enzyme liked immuno sorbant assay (ELISA) method to determine the level of IL 2 in peripheral blood of 30 patients with herpes zoster.\ Results\ There was a significant decrease of CD + 4,CD + 4/CD + 8 and IL 2( t= 2.89 -5.64,P <0.01),and increase of CD + 8( t=3.26,P <0.01)in the peripheral blood of patients with herpes zoster. \ Conclusion\ T lymphocyte subgroup and IL 2 play an important role in the pathogenesis of herpes zoster.