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关于胃、食道、肠、乳腺、宫颈等组织癌变细胞红外光谱测定方法的研究 被引量:3

Determination of Canceration Cells of Stomach, Esophagus, Enteron, Lacteal Gland and Cervical Carcinoma with Fourier Transform Infrared Spectrometry
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摘要 利用傅里叶变换红外光谱 (FTIR)高分辨手段 ,对正常人的细胞和五千余名 (包括胃癌、食道癌、肠癌、乳腺癌、宫颈癌 )患者的细胞进行了对比研究 ,初步得出此方法能在分子水平上揭示出肿瘤细胞与正常细胞的明显差别 ,并且通过谱图解析 ,可直接阐明引起谱图变化的主要原因、细胞癌变的可能机理 ,从而对病程进行预测 。 A new method for determining the canceration cells has been proposed. By means of the high resolution of Fourier transform infrared spectrometry, we have conducted the comparison and study on the normal human cells and those of more than 5000 patients suffering from the cancer. It has preliminary concluded that this method can explain the obvious difference between the cancer cells and the normal ones from the molecular level. Morever, through the interpretation of the spectra, it can directly explain the the main reasons causing the change of the spectra, the possible mechanism of the cells canceration and thus the course of the illness can be forcasted and a bright future for diagnosing cancer in early stage is developed.
出处 《现代科学仪器》 2001年第3期46-47,共2页 Modern Scientific Instruments
基金 河北省自然科学基金资助项目
关键词 傅里叶变换红外光谱 宫颈癌 癌变细胞 胃癌 食道癌 肠癌 乳腺癌 Fourier transform infrared spectrometry cervical carcinoma canceration cells
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参考文献4

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同被引文献34

  • 1慈云祥,高体玉,董建强,阚秀,郭振泉.乳腺良、恶性组织中蛋白质二级结构的Fourier变换红外光谱研究[J].科学通报,1999,44(17):1861-1866. 被引量:10
  • 2Peter R Griffiths,杨虎生,李庆波,凌晓锋,王健生,杨丽敏,徐怡庄,翁诗甫,吴瑾光.红外光谱法和主成分分析法用于胃组织癌变的检测(英文)[J].光谱学与光谱分析,2004,24(9):1025-1027. 被引量:11
  • 3孙素琴,谢莱军,胡鑫尧,白逸秋,赵立文.Micro-FTIR法研究肺癌细胞组织内蛋白质二级结构[J].光谱学与光谱分析,1995,15(1):49-51. 被引量:8
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