摘要
用薄层色谱波对解热止痛片(APC片)中3和成分进行了分离,展开了剂为苯-乙醚-冰乙酸-甲醇(120∶60∶18∶1),展开结果:阿斯匹林Rf=0.84,非那西汀Rf=0.46,咖啡因Rf=0.17。对分离产物进行了FT-IR和PFT-H-NMR研究,结果表明,分离产物纯度较高。分离充分,效果满意。
Three components (aspirin, phenacein and caffeine) in APC tablets were separated by thin layer chro-matography with the mobile phase consisting benzene-ether-acetic acid-methanol (180:60:18:1), then determined by IR and NMR. The result was: aspirin Rf=0. 84; phenacetin Rf = 0. 46, caffeine Rf=0. 17. A thorough separation was proved by IR and NMR spectrum. The method was simple, rapid and reliable.
出处
《现代仪器》
2001年第4期31-34,共4页
Modern Instruments
