姜堰市男性肺癌危险因素的病例对照研究

A Contrast Study of the Risky Factors of Male Lung Cancer in Jiangyan

目的 研究姜堰市男性肺癌危险因素 ,为肺癌的预防监测提供依据。方法 1999年 8月～ 2 0 0 0年 6月间 ,对 181例年龄范围在 2 4～ 86岁肺癌生存病例进行问卷调查。按 1∶1配对 ,调查内容包括一般情况、居住环境、生活习惯、饮食嗜好、既往疾病及家族史等方面 110个问题。采用比值比来估计各危险因素与肺癌的联系强度 ,用Logistic回归模型做单因素和多因素分析 ,筛选出专业上有意义的肺癌危险因素。结果 与肺癌发病有关的变量 4个 ,分别为吸烟、呼吸系统疾病史、精神因素、饮酒。保护因素为良好的体质指数等。结论 吸烟、呼吸系统疾病、精神压抑、饮酒是具有统计学意义的肺癌危险因素 ,良好的体质指数是肺癌的保护因素。

Objective By studying the risky factors of lung cancer in Jiangyan,evidences for further monitoring of the risky factors were provided.Methods A total of 181 male survivors (age ranges from 24～86 years old)of lung cancer were surveyed by questionnaire,matched 1∶1 with controls,from August 1999 to June 2000.There were totally 110 questions in the questionnaire.The survey included general conditions,living environment,diet habit,living style,disease and family history,etc.Correlation power of all the risky factors and lung cancer was evaluated by the odd ratio(OR).Logistic regression model univariate and multivariate analysis was used to choose significant lung cancer risky factors in specialty.Results Smoking, a history of respiratory disease,depression,drinking are 4 main variants related to the genesis of lung cancer.Better body constitution indexes,etc are protective factors.Conclusions Smoking,a history of respiratory disease,drinking and depression are statistically significant lung cancer risky factors,better body constitution indexes are the protective factors of lung cancer.