自动递增刺激记录大鱼际肌运动单位估数及其可重复性

Recording estimation of thenar motor units and its reproducibility by fully automated incremental stimulating

目的 :建立自动递增刺激记录正中神经支配的大鱼际肌运动单位估数 (motorunitnumberestimation ,MUNE)正常值并研究其与年龄、性别的关系和该技术的重复性。方法 :用自动递增刺激记录技术估测正中神经支配的大鱼际肌运动单位数 ,检测无神经肌肉病变的正常人 6 0名 ,年龄 2 0～ 88岁 ,平均 5 0 33± 2 0 81岁。结果 :①正常人正中神经支配的大鱼际肌MUNE为 30 0± 83个 ,三个年龄组的MUNE分别为 35 3± 6 3个 (2 0～ 39岁 )、32 2± 5 4个 (4 0～ 5 9岁 )、2 16± 5 9个 (6 0～ 88岁 ) ;②正常人大鱼际肌MUNE与年龄呈负相关 ,与性别无关 ,6 0岁以上组大鱼际肌MUNE比 6 0岁以下各组明显减少 (P <0 0 0 1) ;③大鱼际肌MUNE重复性实验两次检查值相差不显著 (P =0 3)。结论 :自动递增刺激记录正中神经支配的大鱼际肌MUNE为 30 0± 83个 ,随年龄的增大持续性下降 ,特别在 6 0岁后运动单位数下降明显 ,运动单位估数应考虑年龄因素。大鱼际肌MUNE有良好的可靠性和重复性 ,与性别无关。

Objective:To establish the normal value of motor unit number estimation (MUNE) of the mediannerve innervated thener muscles, to study its relationship with the age and sex and test the reproducibility of the technique.Methods:A fully automated incremental stimulating technique was used to estimate the motor unit number of median innervated thenar muscles, 60 normal subjects without nerve and muscle disease were detected.Results:①The normal MUNE value of median innervated thenar muscles was 300±83(50 33±20 81years old) MUNE of and three age groups were 353±63(20-39years old)、322±54(40-59years old) and 216±59(60-88years old) respectively;②The MUNE value of median innervated thenar muscles had negative correlation with age and had no correlation with sex. MUNE value of median innervated thenar muscles decreased significantly in subjects above the age of 60 as compared with those with age less than 60(P<0 001).MUNE difference of thenar muscles in two times of test were not significant(P=0 3).Conclusions:The MUNE of median nerve innervated thenar muscles recorded by automatic incremental stimulating was 300±83.It might be decreased with the increase of ages,esp in persons with the age above 60 years. Age should be taken into consideration in MUNE recording. MUNE of thenar muscles has good reproducibility and reliability and have no correlation with sex. [