肺容量对氦氧混合气和对高原环境的反应

A REACTION OF VITAL CAPACITY ON HELIUM-OXYGEN MIXTURE AND ALTITUDE ENVIRONMENT

目的 :比较肺容量对氦氧混合气体和对高原环境的反应 ,探讨呼吸氦氧混合气体后肺活量 ,尤其是补呼气容积大幅增高的现象 ;方法 :测定呼吸氦氧混合气体前后的肺活量、初呼气容积和深吸气量 ,并比较它们的变化 ;结果 :呼吸氦氧混合气体后肺活量、补呼气容积较呼吸空气时有明显的增加 ,且两者相比有显著性差异 (P <0 .0 5 ) ,深吸气量呈减少变化 ,但无显著差异 (P >0 .0 5 ) ,其中肺活量平均增加 1 9.2 % ,补呼气容积平均增加87.3 % ,深吸气量平均减少 7.3 9% ;结论 :呼吸氦氧混合气体可令肺活量及初呼气容积大幅增高现象可能是肺功能研究方面一个新的重要发现 ,据推测这可能是氦参与了一些未知的生物学反应的结果 ;另一方面 ,这一现象表明 ,我们对肺弹性的认识尚不充分 。

To study the relationship between vital capacity and helium-oxygen mixture inspiration and altitude environment to explore changes of vital capacity and expiratory reserve volume (ERV).Method:64 cases non-smoking healthy adults(32 men,32 women) were included in this report.Before and after breathing helium-oxygen mixture,the vital capacity,ERV and deep breathing capacity were determined.Results:The vital capacity and ERV were increased remarkably (P<0.05) cmparared with breathing air.And the decreased deep breathing capacity had no a difference (P> 0.05 ).Vital capacity and ERV increased averagely about 19.2% and 87.3% separatly.Conclusion:The results reggest that the helium could take part in some biological reaction of pulmonary function under hypoxia environment.