糖代谢异常患者左心室舒张功能减退的危险因素

RISK FACTORS OF IMPAIRED CARDIAC DIASTOLIC FUNCTION IN PATIENTS WITH ABNORMALITIES OF GLUCOSE METABOLISM

为分析糖代谢异常患者左心室舒张功能异常的相关因素 ,选择 40～ 75岁中老年男性患者 6 3例 ,其中正常糖耐量 (NGT)、糖耐量减低 (IGT)、2型糖尿病 (2TDM )患者分别为 2 0、2 2、2 1例 ,记录常规二维超声结果及二尖瓣和肺静脉血流频谱数据及测定有关生命体征、生化、胰岛素 (INS)指标及DM患者病程。用多元线性回归分析法判断多普勒血流频谱数据与各指标间的关系。结果显示 。

To investigate the clinical risk factors of cardiac diastolic dysfunction in type 2 DM, Doppler echocardiographic examinations were performed on 63 male patients.With a routine 2 dimensional echocardiograph, mitral and pulmonary venous flow velocity were recorded. The patients were classified into DM, IGT and NGT based on well standardized criteria of WHO. All analyses were performed by the SPSS/PC or Windows Release 9.0 Statistical Package. The risk factors of impairment of diastolic function were analyzed by regression. Results showed that the levels of blood glucose and insulin were independent risk factors for diabetic cardiac diastolic dysfunction.