1[1]Doong SL, Tsai CH, Schinazi RF, et al. Inhitibition of the replication of hepatitis B virus in vitro by 2', 3'-dideoxy-3 '-thiacytidine and related analogues. Proc Natl Acad Sci USA, 1991,88: 8495 ～8499
2[2]Tyrrell DLJ, Fischer K, Sayani K, et al. Treatment of chimpanzees and ducks with lamivudine, 2'-3'-dideoxy-3'-thiacytidine, results in a ropid suppression of hepadnaviral DNA in sera. Clin Invest Med, 1993,16( Suppl ) Abs. No. 487:B77
3[3]Yao F,Terrault N, Freisc C, et al. Lamivudine treatment is beneficial in patients with severely decompensated cirrhosis and actively replicating hepatitis B infection awaiting liver transplantation: a comparative study using a matched, untreated cohort. Hepatology,2001,34:411 ～416
4[6]Hoofnagle JH, Lan D. New therapies for chronic hepatitis B. J Viral Hepat, 1997,4(Suppl 1):41 ～45
5Pluda JM,Cooley TP,Montaner JSG et al.Aphase study of 2 deosy 3 thiacytidine (lamivudime) in patients with advanced human immunodeficiency virus infection. J Imfoct Dis . 1995
6Chang CN,Skalski V,Hua Zhou J et al.Biochcmical pharmical of (+)-and-(-)2 ’ 3 ’ -didcoxy-3 ’ -thiacytidine as antihepalitis B Virusagents. Journal of Biological Chemistry . 1992
7Villeneuve JP,Condreay LD,Willems B et al.Lamivudine treatment for decompensatcd cirrhosis resulting from chronic hepatitis B. Hepatology . 2000
8Chien RN,Liaw YF,Atkins M.Pretherapy alanine transaminso levels as a detrminant for hepatitis B antigne seroconversion during lamivudine thotapy in patients with chronic hepatitis B. Hepatology . 1999
9Tassopoulos NC,Volpes R,pastore G et al.ETTicaey of lamivudinein patlents with hepatitis B e AntigenNegative hepatitis B Virus DNA positive (Precore Matsnt ) Chronic Hepatitis B. Hepatology . 1999
10Dienstag JL,Petillo RP,Schiff ER et al.Double for chronic hepatitis B. N Dnal J Med . 1995
