喉返神经吻合术治疗喉外展麻痹的实验研究

Experimental study on the recurrent laryngeal nerve anastomosis for the treatment of laryngeal abductor paralysis

目的 探讨喉麻痹的神经吻合治疗术效果。方法 造成犬单侧喉返神经干完全性损伤 ,同时切断其喉内收肌支干 ,即行同期膈神经—喉返神经神显微神经吻合术 ,造成膈神经对同侧喉返神经外展肌支的单一支配。对正常、神经切断后立即及神经吻合术后 4月环杓后肌进行肌电功能学及形态学检查。结果 神经吻合术后 4月 ,环杓后肌肌电活动恢复 ,运动神经终板体系已开始形成 ,但要达到完全正常水平 ,仍需一定恢复时间。结论 喉返神经吻合术能有效治疗喉外展麻痹。

Objective To explore the effect of the reinnervation operation for the treatment of the laryngeal paralysis.Methods The unilateral recurrent laryngeal nerve(RLN)and its adducent branch were cutted at the same time.The nervous reinnervation between the phrenic nerve and the RLN was then realized on purpose to make the phrenic nerve purely innervating the posterior cricoarytenoid muscle (PCA).The morphology and electromyography examination were realized at the different time of the experiment.Results Four months after the operation,the morphology and electromyography examination on the PCA showed that the new nerve-ending system began to recover.It still needed some time to reach to normal level.Conclusions The nervous anastomosis of the recurrent laryngeal nerve is effective for the treatment of laryngeal abductor paralysis.