DIVERSITY OF PATHOLOGICAL PAIN: NEW EVIDENCE FROM THE BEE VENOM MODEL

There has been increasing experimental evidence showing that the clinical pathological pain differs greatly from physiological pain. The former is characterized by its clinical diversity in manifestations referred to as: (1) persistent spontaneous pain (pain lasts without external stimulation); (2)hyperalgsia (enhanced pain sensation following normally noxious heat or mechanical stimuli);(3) allodynia (abnormal pain evoked by normally non-painful stimulation or touch-evoked pain). Moreover, hyperalgesia or allodynia can be further classified