超声彩色室壁动力学对心肌梗死范围定量的实验研究

EXPERIMENTAL STUDY ON MYOCARDIAL INFARCT SIZE WITH COLOR KINESIS ECHOCARDIOGRAPHY

目的 :验证超声彩色室壁动力学 (CK)分析技术判断心肌梗死的准确性。方法 :结扎犬冠状动脉 (冠脉 )造成实验性急性心肌梗死模型 ,应用超声CK分析技术与病理解剖的结果进行对比性研究。结果 :结扎犬冠脉前超声CK图像由红 黄 绿 蓝色组成 ,色彩分布均匀 ,心内膜彩色移位 (SEM )值为 7 98～14 5 3mm :结扎犬冠脉后造成实验性急性心肌梗死时超声CK图像绿 蓝色完全消失 ,仅遗留红 黄色 ,SEM值为 1 2 7～ 6 45mm ,与结扎前对比明显减少 (P <0 0 5 )。超声CK图像检测的心肌梗死范围为 (2 6 2±4 8)mm2 ,病理解剖测量为 (2 2 5± 4 7)mm2 ,两者对比显著相关 (r =0 .92 64,P <0 0 1)。结论 :超声CK图像有助于急性心肌梗死定性、定量诊断。

Objective:To analyse size of myocardial infarction by color kinesis echocardiography(CK).Methods:The animal models of acute myocardial infarction were made by blocking the coronary arteria of dogs and a correlative study was made between results of CK and pathology.Results:The images of normal dogs consisted of four colors (red yellow green blue),which evenly dispersed,and the SEM was 7.98～ 14.53 mm.The images of dogs with acute myocardial infarction only consisted of two colors (red yellow),and the green blue disappeared completely,and the SEM was 1.27～6.45mm,which decreased significantly ( P<0.05). The infarct size examined by CK was (26.2±4.8)mm 2,and (22.5±4.7)mm 2 by pathology,they were significantly correlative ( r=0.9264,P<0.01). Conclusion:The images of CK can help to analyse the infarct size qualitatively and quantitatively.