异丙酚对气管切开插管心血管功能的影响

Hemodynamic variables throughout tracheotomy under propofol anesthesia

目的 观察异丙酚对喉部手术气管切开插管时心血管功能的影响。方法 选择喉部手术需气管切开术病人 2 0例 ,随机分成异丙酚组 (P组 )和对照组 (C组 )。P组在异丙酚麻醉 (切皮前静注 1～ 2mg·kg-1)和局麻下 ,C组在局麻下行气管切开术。观察病人收缩压 (SBP)、舒张压 (DBP)、心率 (HR)的变化。结果 C组SBP、DBP在气管插管时较P组升高 (P <0 0 5 )。C组DBP在切皮时、插管后 1min、3min较P组升高 (P <0 0 5 )。C组HR在切皮时较P组升高(P <0 0 5 )。两组血氧饱和度的变化无显著性差异 (P >0 0 5 )。

Objective To observe hemodynamic variables throughout the peri operative period of tracheotomy under propofol anesthesia. Methods 20 patients undergoing tracheotomy whose systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were observed were divided into two groups randomly: propofol group(group P) administered propofol 1～2 mg·kg -1 and local infiltration anesthesia before skin incision and compared group(group C) only performed local infiltration anesthesia with 5 g·L -1 lignocaine. Results SBP and DBP in group C were higher than in group P ( P< 0 05) during intubation. DBP in group C at the time of incision, after intubation 1 min and 3 min were higher than in group P ( P <0 05). HR in group C was higher when incision was cut. The variables of SpO 2 did not show significant difference between the two groups. Conclusion Cardiovascular effects were suppressed during tracheotomy when propofol was administered.