壳聚糖澄清剂的脱乙酰度及残留量研究

Studies on degree of deacetylation of chitosan and its residual amount left over in clarified products when used as a clarificant

目的 对壳聚糖澄清剂的脱乙酰度及精制后的中药水提液中壳聚糖的残留量进行了探讨。方法 用线性滴定测定壳聚糖 (游离胺基 )的含量。结果 壳聚糖澄清剂的脱乙酰度约 80 % ,在澄清液中壳聚糖残留量小于0 .0 10 %。结论 壳聚糖作为精制中药水提液的澄清剂是可行的。

Object To study the degree of deacetylation of chitosan and its residual amount left over in the clarified products when chitosan was used as a clarificant. Methods The free amino group in the deacetylated chitosan was determined by linear titration. Results The degree of deacetylation of chitosan was found to be about 80%. The residual amounts left over in the clarified products were lower than 10 -4 . Conclusion The results suggested that it is feasible to use chitosan as a clarificant for refining water extract of TCM.