摘要
目的:对甲磺酸甲氟哌酸糖衣片体外溶出度测定方法进行考察,为评定和控制药品内在质量提供依据。右法:采用紫外法对甲磺酸甲氟哌酸糖衣片溶出度进行测定,并对转篮法和浆法两种测定方法进行了比较。结果:两种测定方法的溶出参数 T50、Td、m经成组比较t检验,差异显著(P<0.01)。结论:使用转篮法测甲磺酸甲氟哌酸糖衣片效果较好。
OBJECTIVE: To study the dissolution of pefloxacin tables. METHODS: The dissolution rate of pefloxacin tablets was determined by ultraviolet spectrophotometry. At the same time, rotating basket method and oaring method ware compared. RESULTS: There was signifficant difference (P <0. 01) in T50 and Td between rotating basket method and oaring method. CONCLUSION: Using rotating basket method to test dissolution is better than using oaring method.
出处
《药学实践杂志》
CAS
2001年第5期293-295,共3页
Journal of Pharmaceutical Practice