微波促进芳基叠氮与α-酮基膦叶立德的快速反应

Rapid reaction of aryl azides with α-keto phosphorus ylides by microwave irradiation.

本文报道了以硅胶作支持剂 ,在微波辐射下进行芳基叠氮与 α-酮基膦叶立德的反应 ,以中等至良好的产率生成相应的 1-芳基 - 1,2 ,3-三氮唑化合物 .与传统方法相比 ,具有操作简便、反应时间短的优点 .

Aryl azides react with \%α\%\|keto phosphorus ylides using silica gel as supporter and under microwave irradiation to afford corresponding 1\|aryl\|1,2,3\|triazoles in moderate to good yields. As compared with the traditional method, microwave irradiation can promot the work more facilely with high efficiency. The reactional mechanism and structure characteristiscs of the products also have been discussed.