N-苯基-2,2,6,6-四氯环己亚胺的催化合成

Catalytic Synthesis of N-phenyl-2,2,6,6- tetrachlorocyclohexaneimine

以 2 ,2 ,6,6-四氯环己酮为原料 ,在催化剂存在下 ,合成了 N-苯基 -2 ,2 ,6,6-四氯环己亚胺。通过对催化剂、溶剂用量、反应时间、反应温度等因素的考察 ,得到了适宜的工艺条件 :在 n(酮 )∶n(苯胺 )∶n(催化剂 ) =1∶ 5∶ 1 .5(摩尔比 ) ,反应温度为 1 0～ 2 0℃ ,反应时间为 3.5h的条件下 ,收率为 80 %。

N phenyl 2,2,6,6 tetrachlorocyclohexaneimine is synthesized through condensation of the 2,2,6,6 tetrachlorocyclohexanone with an aniline in the presence of a catalyst.The influence of different catalysts,amount of solvent,mol ratio of materials,reaction time and reaction temperature etc. on the product yield is tested.The 80 cent of the yield of condensation product was obtained under the temperature 10-20℃ and reaction time 3.5 h and the mol ratio of 2,2,6,6 tetrachlorocyclhexanone∶aniline∶catalyst=1∶5∶1.5.