1997～1999年四川省急性驰缓性麻痹病例实验室监测结果分析

Analysis of Result of Surveillance on Acute Flaccid Paralysis Case in Sichuan,1997～1999.

目的 为我省消灭脊髓灰质炎提供证实资料。方法 按世界卫生组织 (WHO)《脊髓灰质炎病毒检验手册》进行实验。结果 1997～ 1999年四川省AFP病例共收到 832例标本 ,分离出脊灰病毒 41株 ,总阳性率≥ 15 90 % ;非脊灰肠道病毒 (NPEV)最低 7 95 %。 41株脊灰病毒中P2 和含P2 混合型为 2 6株 ( 2 6 /41) 在零剂次服苗的 13例AFP病例中P2 和含P2 更是高达 12株 ( 12 /13)。分离出脊灰的AFP病例 ,最少 6 0 0 0 %是男性 ,70 0 0 %≤ 5岁。AFP报告发病率最低 1 2 4/10万 ,合格便采集率最低 80 6 0 % ,送便及时率最低 86 70 % ,分离结果 30天报告率最低 81 3 %。结论 我省脊灰实验室各项监测指标全部达到WHO的要求 。

Objective After the iplementation of caute flaccid paralysis(AFP) surveillance,for 10 gears,poliomyelitis eradication come into certification stage in nation as well as in Sichuan,provincial surveillance provides information for eradication documentation.Methods Test according the 'manual of poliovirus Detection'by WHO.Results 832 stool specimens form AFP cases were received in provincial laboratory in 1997～1999,of which 41 were polio postitive isolates,and postitive rate was ≥15 90%;non polio enterovirus(NPEV) isolation rates was at least 7 95%.Most of the polio postitive isolates were type Ⅱ and its mixture(26/41).12 type Ⅱ polio positive isolates belonged to AFP cases of non vaccine administration.Male and children under 5 years bore great portion in polio postitive isolates respectively.AFP case reporting rate,adequate specimen collection rate and result feedback rate within 30 days after specimen reception un provincial laboratory were at least 1 24/100 000,80 60% and 81 35% respectively.Conclusions All surveillance targets met WHO requirement.Provincial laboratory had been accredited by Ministry of Health and WHO.