摘要
目的 :优选三黄胃血平胶囊制备工艺。方法 :采用有效成份大黄素 ,小檗碱 ,黄芩苷含量和药效双向指标控制优化条件。结果 :优选的工艺为 :95 %乙醇提取小檗碱 ,白芨水浸 70 %乙醇沉淀 ,大黄 ,黄芩 ,甘草水煎 6 0 %乙醇沉淀。所制胶囊具有较强的药理效应。结论 :工艺合理 。
Objective: To select the optimum prepartion procedure for Sanhuangweixueping, Capsules. Methods: The optimum conditions were selected with the contents of active components: emodin, berberine, and baicalin as markers. Results: The optimum preparation procedure was: berberine was extracted with 95% alcohol. Rhizoma Bletillae was immersed with water, then precipitated with 70% alcohol. Radix et Rhizoma Rhei, Radix Scutellariae and Radix Glycyrrhizae were decocted, then precipitaed with 60% alcohol. Sanhuangweixueping Capsules prepared with the optimum preparation procedure possessed stronger pharmacological effect. Conclusion: The optimum prepartion procedure is reliable and the extraction ratio of active compoents is high.
出处
《中成药》
CAS
CSCD
北大核心
2001年第6期391-394,共4页
Chinese Traditional Patent Medicine
关键词
三黄胃血平
大黄
工艺优选
胶囊
药理
中药
Sanhuangweixueping Capsules
Radix et Rhizoma Rhei
preparation procedure
