1Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature, 1994; 372:425
2Zhongmin M, Gingerich RL, Dsnyisho JV, et al. Radioimmunoassay of leptin in human plasma. Clin Chem, 1996; 42:942
3Tartaglia LA, Dembski M, Weng X, et al. Identification and expression cloning of a leptin receptor, OBR. Cell, 1995; 83:1263
4Pelleymounter MA, Cullen M J, Baker MB, et al.Effects of the obese gene product on body weight regulation in ob/ob mice. Science, 1995; 269:540
5Campfield LA, Smith FJ, Guisez Y, et al. Recombinant mouse ob protein evidence for a peripheral signal linking adiposity and central neural networks. Science, 1995; 269: 543
6Chen H, Charlat O, Tartaglia LA, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell, 1996; 84:491
7Kieffer TJ, Heller RS and Habener JF. Leptin receptors expressed on pancreatic β cell. Biochem Biophysi Res Commun, 1996; 224:522
8Emilsson V, Liu YL, Cawthorne MA, et al. Expression of the functional leptin receptor messenger RNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes, 1997; 46:313
9Saladin R, De Vos P, Guerre-Millo M, et al. Transient increase in obese gene expression after food intake or insulin administration. Nature. re, 1995; 377:527
10Cusin I, Sainsbury A, Doyle P, et al. The ob gene and insulin: a relationship leading to clues to the understanding of obesity. Diabetes, 1995; 44:1467