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氯氮平对Ⅰ、Ⅱ型精神分裂症认知功能缺陷的影响 被引量:5

The Efficacy of Clozapine Trefatment on Cognitive Impairments of Patinets with TypeⅠ,Ⅱ Schizophrenia
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摘要 Objective:To understand the change of cogn itive function in type Ⅰand Ⅱschizophrenic patients after Clozapine treatment.Methods:Forty-six four-week during free patients met with the criteria of schizop hrenia were included in this study .Twenty-eight of these patients were diagnosed as type Ⅱshizophrenia. WCST,SAPS ,SANS and PANSS were used to assess these patients before and after eight weeks Clozapine treatment. R esults:Total trails to four categories (TT),Persistent error s (PE) and non-persistent errors (NPE) of WCST improved significantly after Clozapine treatment. Conclusion:The results revealed significant cognitive defi cits in type Iand II schi zophrenic patients,which were significantly improved by clozaoine treatment. Objective:To understand the change of cogn itive function in type Ⅰand Ⅱschizophrenic patients after Clozapine treatment.Methods:Forty-six four-week during free patients met with the criteria of schizop hrenia were included in this study .Twenty-eight of these patients were diagnosed as type Ⅱshizophrenia. WCST,SAPS ,SANS and PANSS were used to assess these patients before and after eight weeks Clozapine treatment. R esults:Total trails to four categories (TT),Persistent error s (PE) and non-persistent errors (NPE) of WCST improved significantly after Clozapine treatment. Conclusion:The results revealed significant cognitive defi cits in type Iand II schi zophrenic patients,which were significantly improved by clozaoine treatment.
出处 《中国临床心理学杂志》 CSCD 2001年第3期210-211,共2页 Chinese Journal of Clinical Psychology
关键词 氯氮平 精神分裂症 认知功能缺陷 Schizophrenia cognitive function clozap ine
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