舌体癌121例治疗结果分析

Analysis on the curative effect of 121 oral tongue carcinomas

目的 回顾性分析比较手术治疗和放射治疗对舌体癌远期疗效的影响以及相关因素。方法 1987年 3月至 1995年 6月收治的 12 1例舌体鳞癌接受了根治性治疗。2 5例采用根治性体外放射治疗 (R) ,6 2例为联合根治手术治疗 (S) ,34例为联合根治手术加术后放射治疗 (S +R)。用Kaplan Meier方法分析疗后生存率及局控率。结果 全组病例总的 5年总生存率为 46 .40 % ,三组病例的 5年总生存率分别为R组 2 8.88%、S组 42 .0 5 %和S +R组 6 5 .5 6 % ,具有显著性差异 (P =0 .0 0 5 1)。结论 联合根治术加术后放射治疗对于舌体癌是一种较为有效的治疗手段。术后放射治疗可以提高手术治疗的局部控制率和远期生存率。

Objective To retrospectively analyze and compare the effects of surgery and radiation on oral tongue carcinoma.Methods 121 cases of oral tongue squamous cell carcinoma were treated from March 1987 to June 1995.25 patients were treated with radiotherapy alone,62 cases were treated with combined radical operation and 34 patients received surgery plus postoperative radiotherapy.Kaplan-Meier method was used in the survival and local control analysis.Results In all patients the 5-year survival rate was 46.40%.The 5-year survival rates for radiation alone,surgery alone and surgery plus postoperative radiotherapy groups were 28.88%,42.05% and 65.56%(P=0.0051)respectively.Conclusion Surgery plus postoperative radiotherapy is an efficient method for oral tongue carcinoma.Postoperative radiotherapy could improve the survival rate and local control rate for oral tongue carcinoma.