口腔白斑癌变与吸烟关系的初步探讨

PRELIMINARY STUDY ON THE RELATIONSHIP BETWEEN SMOKING AND MALIGNANT TRANSFORMATION OF ORAL LEUKOPLAKIA

目的 :初步探讨口腔白斑的重度上皮异常增生及癌变与吸烟的关系。方法 :通过对口腔白斑患者中吸烟者与不吸烟者的临床分型、组织病理变化和吸烟者吸烟情况等临床资料进行综合分析、比较。结果 :吸烟者白斑的重度上皮异常增生和癌变发生率明显高于不吸烟者 ,并且随着吸烟包年数的增加 ,吸烟者的重度上皮异常增生和癌变发生率也增高。结论

Objective:To study the relationship between smoking and malignant transformation of oral leukoplakia.Methods:The clinical data of non smoking and smoking patients such as clinical type,various epithelial dysplasia and the smoking state of smokers was analysed.Results:The incidence of severe epithelial dysplasia and malignant transformation of smokers with oral leukoplakia was higher than that of non smokers.The more they smoked,the more frequently the severe epithelial dysplasia and the malignant transformation occured.Conclusion:The present study indicates that there might be some correlation between smoking and canceration of oral leukoplakia.