不同强度的科里奥利加速度刺激对人体主观感觉及眼震的影响

The influence of Coriolis acceleration magnitude on human oculomotor and perceptual responses

目的 观察不同强度的科里奥利加速度刺激对人体主观感觉及眼震的影响 ,以探讨科里奥利错觉与不同强度的科里奥利加速度刺激间的相关性及眼震电图作为反映科里奥利错觉客观指标的可行性。 方法 在 VTS- 型前庭功能评定系统上 ,12名男性青年健康志愿者 ,每人按随机次序分别接受三次不同强度 (π2 / 30、π2 / 2 0、π2 / 15 cm/ s2 )的科里奥利加速度刺激。每次刺激后休息 5 m in再进行下一次刺激。在刺激过程中嘱受试者用秒表记录下主观感觉 (即科里奥利错觉 )持续时间 ,并实时记录下受试者的眼震电图 (包括水平眼震与垂直眼震 ) ,刺激后询问受试者的错觉形态。三次刺激完后让受试者对三次的错觉强度进行比较。 结果 不同强度的科里奥利加速度刺激对错觉形态具有一定影响 ,错觉持续时间、错觉强度随科里奥利加速度的增加而增加 (P<0 .0 5 ) ,不同科里奥利加速度刺激下的眼震电图各参数差别均无显著性意义 (P>0 .0 5 )。 结论 科里奥利错觉强度、错觉持续时间随科里奥利加速度的增加而增加 ,错觉形态也随之有一定的改变 。

s Objective To investigate the influence of different Coriolis acceleration levels on human subjective sensation and nystagmus, to explore the correlation between Coriolis illusion and Coriolis acceleration magnitude and to define the feasibility of using nystagmus parameters as the objective index of Coriolis illusion. Methods Twelve healthy young male volunteers served as subjects. Using VTS III type vestibular function evaluation system, each of them underwent 3 different levels Coriolis acceleration stimulation(π 2/30、π 2/20、π 2/15 cm/s 2) at random sequence with 5 min rest between 2 stimulations. During the stimulation they were asked to record the duration of subjective sensation of Coriolis illusion. At the same time ENGs were recorded. After each stimulation, the pattern of illusion was asked. The intensities of subjective sensations induced by 3 levels of Coriolis acceleration were compared. Results Different level of Coriolis stimulation had some influence on the pattern of the illusion. The intensity and the duration of the illusion increased along with the levels of Coriolis acceleration stimulation. No significant differences of ENG parameters in response to different levels of Coriolis stimulation were observed. Conclusion The intensity and the duration as well as pattern of Coriolis illusion were influenced by magnitude of Coriolis acceleration. However, no significant changes were observed on ENG parameters.