儿童中枢神经系统肿瘤(附766例分析)

Central Nervous System Tumors in Children——Analysis of 766 Cases

目的:探讨儿童中枢神经系统肿瘤的发病特点.方法:对华山医院1986～1998年儿童中枢神经系统肿瘤766例,进行回顾性分析.结果:本组占同期中枢神经系统肿瘤病例数的6.14%.部位:颅内725例,其中幕上499例,幕下276例,椎管内41例.组织学分类:前三位分别是:星形细胞性肿瘤(199例,占26.0%);颅咽管瘤(115例,占15.0%);髓母细胞瘤(101例,占13.2%).性别:男孩多见.发病涉及各年龄组,病例数随年龄的增长而增加.结论:儿童中枢神经系统肿瘤位于幕上者多于幕下,颅内肿瘤以星形细胞性肿瘤最常见,男孩比女孩好发,为1.50:1.

Aim:To discuss the characteristics of central nervous system tumors in childhood.Methods:The 766 cases of pediatric patients with intracranial and intraspinal neoplasms during last 13 years were retrospectively analyzed. Results: Tumors of the central nervous system in childhood acounted for 6.14 % of total cases in our unit during the same period. There were 725 caes of intracranial tumors, among which the supratentorial tumors were 449 cases and infratentorial tumors were 276 cases. There were 41 cases of intraspinal neoplasms. The histopathological ranking of the central nervous system tumors were : astrocytic tumors (199 cases, 26. 0%); craniopharyngioma (115 cases, 15.0%); medulloblastoma (101 cases, 13.2%), and boys were more frequent. Conclusion: The morbidity of supratentorial tumors in childhood was much higher than that of infratentorial tumors. Astrocytoma was the most common type. The incidence was male dorminant, M:F= 1.50:1.