滋养细胞肿瘤患者血清和头发中六种元素含量的变化

Change of Six Elemental Contents in Serum and Hair of Patients with Trophoblastic Tumor

本文报告了滋养细胞肿瘤患者血清(36例)和头发(42例)中 Zn、Cu、Fe、Mn、Ca 和 Mg的测定结果。与当地同期正常妊娠者比较,患者血清 Zn 降低,Cu、Cu/Zn 值明显升高,并随病情加重而加剧、随病情好转明显回复;患者头发中 Zn 显著减少、Cu/Zn 值亦明显升高。结果提示:发 Zn 结合血 Zn 的测定。对此病的早期发现和诊断有一定价值;血清 Cu、Zn、Cu/Zn 值结合 Cp、HCG 的测定,可作为病情变化、治疗、预后的依据和参考。患者血清 Mn、发 Mn 均明显高于正常妊娠者,值得注意。

We present the results of determining Zn,Cu,Fe,Mn,Ca and Mg in the serum samples of 36 cases and hair samples of 42 cases.Comparing the patients of trophoblastic tumor with the local normal pregnant women in the same period,we found that in the patients' serum the amount of Zn decreased,and the amount of copper and the ratio of Cu/Zn increased evi- dently.They developed or went down along with the patients being worse or better.In the pa- tients' hair the amount of Zn decreased obviously and the ratio of Cu/Zn increased.The re- sults indicated that the determination of Zn in the seum and hair would be of great value in finding and diagnosing the disease early and the determination of Cu,Zn and the ratio of Cu/Zn with CP and HCG would provide a basis for the state of illness and it's prognosis.It was noted that the amount of manganese in the serum and hair of the patients was distinctly higher than those of the contrast.It provided an experimental basis for the prevention, diagnosis,treatment and prognosis of trophoblastic tumor.