摘要
云南锡矿区呼吸道恶性肿瘤高发,为了探明其原因,用含砷、铁、铅等的人工合成混合尘1、2、3号进行 Wistar 大鼠诱瘤实验,结果如下:3个实验组中发生了31例肺肉瘤,发生率22.6%。31例中有28例肺恶性淋巴瘤,占90.2%。此外,发现了3例肺癌,对照组未发现肺良恶性肿瘤。上述结果表明人工合成矿尘1、2、3号对 Wistar 大鼠有致肺肉瘤效应。
There is a high incidence of malignant lung tumor in Yunnan tin mine area.In order to detect the causes,the mixtures of artificial synthetic mine dust containing As,Pb,Fe etc(No. 1,2,3)were used for tumor-inducing experiments on Wistar rats.The results were as follows: 31 lung sarcomas were developed in 3 experimental groups and the incidence was 22.6%.The malignant lung lymphomas developed in 28 of 31 sarcomas,the rate being 90.2%.In addition, 3 cases of lung cancer were found.No benign or malignant lung tumor was found in the con- trol group.The results showed that the artificial synthetic mine dust(No.1,2,3)was related to the lung sarcoma formation on Wistar rats,which is reported for the first time.
出处
《昆明医学院学报》
1991年第4期1-4,共4页
Journal of Kunming Medical College
基金
国家科委基金资助的课题
关键词
矿尘
恶性肿瘤
呼吸道肿瘤
Artifical synthetic mine dust
Respiratory malignant tumor
Tumor-inducing experiment