一氧化氮与肿瘤的发生、发展及转移相关的研究进展

Advances of the research on the correlation of nitric oxide and the generation,development and metastasis of tumors

一氧化氮 (NO)作为一种自由基性质的气体分子 ,参与了肿瘤的发生、发展、转移等过程。NO一方面介导了巨噬细胞、内皮细胞的杀瘤作用 ,另一方面又通过促进血管生成、增加血流量促进肿瘤生成。对NO的深入研究 ,将为探索肿瘤的发生、发展和开辟新的治疗途径带来希望。

Nitric oxide(NO) is a kind of gas with the character of free radical,taking part in the generation,development and metastasis of the tumor.On the one hand,NO kills the tumor via macrophage and endothelial cells.On the other hand,NO accelerates the growth of tumor by promoting the growth of blood vessels and increasing the blood flow. Further study of NO will bring the hope of exploring the generation and development of tumors, and finding the new methods of treatment.