羧甲基壳聚糖金属配合物的研制

Study on the Preparation of Metal Complexes of Carboxymethyl Chitosan

应用水溶性的羧甲基壳聚糖与 Ca2 +、Fe2 +、Zn2 +进行络合制备金属配合物 ,探讨反应时间、温度、羧甲基取代度、溶液离子强度、p H等反应条件对络合的影响 ,考察金属配合物的性质。结果表明 :络合反应的最佳 p H值为 5～ 7;室温下反应 10 min络合量趋于饱和 ;羧甲基壳聚糖对各金属离子络合能力随羧甲基取代度的增大而增强 ,随着体系的离子强度增大而减弱。

By complexation reaction with water-soluble carboxymethyl chitosan and Ca 2+ ?Fe 2+ ?Zn 2+ in solution,the metal complexes of Ca 2+ ?Fe 2+ ?Zn 2+ were preparated.The effects of various factors:reaction time,etmperature,substitution degree of carboxymethyl group,ionic strength and pH value on the reaction were investigated.The results showed that the optimum reaction condition was pH 5~7,time 10 min,the complex capacity of CMCS for metal ions increasing with the substitution degree of carboxymethyl group,decreasing with the ionic strength of solution.