急性脑血管病患者的血清心肌酶谱改变

Changes in Serum Cardiac Enzymogram of Patients with Acute Cerebrovascular Disease

对７０例急性脑血管病通过血清心肌酶谱测定，进行脑－心综合征研究。结果显示：（１）出血组的血清谷草转氨酶（ＧＯＴ）、乳酸脱氢酶（ＬＤＨ）、α－羟丁脱氢酶（α－ＨＢＤＨ）、肌酸激酶（ＣＰＫ）较对照组显著升高（Ｐ＜０．０５和Ｐ＜０．０１）。（２）出血组中累及丘脑、脑干、脑室及蛛网膜下腔者的血清ＬＤＨ、α－ＨＢＤＨ较累及其他部位者升高的幅度更大（ｐ＜０．０５）。（３）出血组中死亡患者的血清ＬＤＨ、α－ＨＢＤＨ明显高于存活者（Ｐ＜０．０１）。探讨了脑－心综合征的发生机制和血清心肌酶谱测定在脑卒中的临床意义。

Based on the determination of serum myocardial enzymography in seventy patients withacute cerebrovascular diseases,cetebro cardiac syndrome has been studied.The resultsshowed that(1)The serum GOT,LDH,α-HBDH and CPK levels of the haemorrhagicgroup were significantly higher than those of normal group (P<0. 05 and P<0.01 ).(2)The range of inerease in the serum LDH and α-HBDH levels of patients in the haemorrhagicgroup with involvement of thalamus,brainstem,cerebral ventricles and subarachnoid spacewas higher than that in those involving other sites(P<0.05).(3)The serum LDH and α-HBDH levels in diseased patients of the haemorrhagic group were markedly higher than thosein the survivors(P<0.01).The pathologic mechanism of cerebrocardiac syndrome andclinical significance of serum enzymographic determination in acute stroke have beendiscussed as well.