高频喷射通气结合胸壁挤压对组胺犬死腔量的影响

^^Effect of High Frequency Jet Ventilation Combined with Chest Wall Compression on Deadspace in Canine with Histamine Infusion

本文观察了高频喷射通气结合胸壁挤压（ＨＦＪＶ＋ＣＷＣ）对组胺致肺损伤犬进行体制呼吸时解剖死腔量（Ｖ）和生理死腔量（Ｖ）的影响，并与单纯高频喷射通气（ＨＦＪＶ）进行比较。结果表明，与ＨＦＪＶ相比，ＨＦＪＶ＋ＣＷＣ时Ｖ、Ｖ、ＦＲＣ和ＰａＣＯ＿２均显著减少（Ｐ＜０．０１），Ｖ＿Ａ和ＶＣＯ＿２均显著增加（Ｐ＜０．０１），而Ｖ＿Ｅ、Ｖ＿Ｔ和ＰａＯ＿２均无显著变化（Ｐ＜０．０５）。提示，ＨＦＪＶ＋ＣＷＣ控制呼吸时，Ｖ和Ｖ的减少是增强ＣＯ＿２排除效能的主要机理之一。

he effects of high frequency jet ventilation combined with chest wall compression（HFJV+CWC ） on deadspace were observed in canine with histamine─induced lund injury during controlled respiration and compared with those of high frequency jet ventilation（HFJV）, The reSults showed that physiologic deadspace （ V）, anatomical deadspace（V）,functional residual capacity and PaCO2 during HFJV+CWC were significantly lowerthan those of HFJV（P<0. 01 ）, Every minute alveolar ventilation and elimination of CO2during HFJV+CWC were obviously higher than those of HFJV（P<0. 01 ）, No significantdifference was observed in every minute ventilation,tidal volume and PaO2（P<0. 01 ）,It issuggested that the decrement of V and V is one of the main mechanisms of enchancingCO2 elimination during HFJV+CWC with controlled respiration.