内皮素在艾灸治疗哮喘豚鼠中的作用

Role of the Endothelin on Guina-pigs with Asthma by the Treatment of Moxibustion

目的 :观察内皮素在艾灸治疗哮喘豚鼠中的作用。方法 :运用放免方法测定哮喘豚鼠及对其艾灸治疗中内皮素 (ET)的含量。结果 :发现豚鼠哮喘血浆中内皮素含量明显升高 ,而经过艾灸治疗后 ,哮喘豚鼠血浆内皮素含量明显降低。结论 :ET可能通过激活磷酯酶 ,影响其代谢产物 ,导致支气管平滑肌收缩 ,并参与了哮喘的发病及病程 。

Objective: to observe the effection of ET on the guinea-pigs with asthma by the treatment of moxibustion. Method: To investigate the contention of ET in the asthmatic guinea-pigs and in the course of the treatment of moxibustion by radioimmunoassay. Result :There was increased amounts of ET in the asthmatic guinea-pigs and by the treatment of moxibustion,the amounts of ET went down obviously. Conclusions: the ET can activate the phosphatide enzyme,affect the production of metabolite,cause the contraction of the smooth muscles of airway,and take part in the occurring and course of asthma,the moxibustion can decrease the amounts of ET in the guinea-pigs with asthma,result in the diastole of the smooth muscles of airway,thus treat asthma.