摘要
目的 采用被动吸烟方法研究香烟烟雾对金黄地鼠胚胎的致畸作用。②方法 应用被动吸烟笼具将不同妊娠时间的金黄地鼠分组进行被动吸烟 ,而后计数每组的胚胎植入数、活胎、吸收胎、死胎、畸胎及畸形数 ,并进行统计学处理。③结果 孕 1～ 6d ,7d ,9d以及 10～ 14d吸收胎加死胎的百分数比对照组略有增加 ,畸胎和畸形数无增加。而孕 8d吸收胎加死胎百分数、畸胎率均比对照组有显著增加 (χ2 =17.2 ,5 1.4,P <0 .0 0 1)。④结论 吸烟对胚胎有致畸作用。
Objective\ To study the tobacco induced teratogenesis on intrauterine development of embryos in pregnant golden hamster by way of passive smoking. \ Methods\ Golden hamsters of different gestational period were exposed to tobacco smoke in different groups ,then the number of implantations,livings,absorbed fetuses,deaths and malformationa were counted for each group and dealt with statistical analysis. \ Results\ Those of the absorbed fetuses and deaths in 1-6days,7days ,9days and 10-14days of gestation were slightly higher than those in the control group. While those of malformations did not increase. The percentage of absorbed fetuses and deaths and malformations at 8 days of gestation were dramatically increased compared with the controls ( χ 2= 17.2, 51.4, P <0.001).\ Conclusion\ Passive smoking has significant teratogenic effects on embryos.
出处
《青岛大学医学院学报》
CAS
2001年第4期291-293,共3页
Acta Academiae Medicinae Qingdao Universitatis
基金
山东省自然科学基金资助项目 (Y98130 42 )
