感染性眼内容炎的预后与病原菌关系的临床分析

Relationship between the prognosis of infectious endophthalmitis and microorganisms

目的 :评价感染性眼内容炎的预后与病原体的关系。方法 :回顾性分析 71例 (71眼 )感染性眼内容炎的病原菌检查、临床处理的结果。结果 :38例 (38眼 )玻璃体标本病原菌培养阳性 ,其中革兰氏阳性球菌 13例 ,革兰氏阴性杆菌 13例 ,真菌 8例 ,革兰氏阳性杆菌 4例。视力达到或好于 5 / 10 0者 11例 ,其中 G+球菌 7例占 5 8.3% ;G-杆菌 2例占 16 .7% ;真菌 2例占 2 5 % ;G+杆菌无一例。结论 :G+ 球菌 ,G- 杆菌是感染性眼内容炎的主要致病菌 ,G+ 球菌感染预后较好 ,G- 杆菌感染预后较差 ,差异有显著性 (p<0 .0 5 )

Objective: To evaluate the relationship between prognosis of infectious endophthalmitis and microorganisms. Methods: An analysis was run retrospectively in 71 cases (eyes) of infectious endophthalmitis on the pathogenic, clinical management and prognosis. Results: vitreous samples were positive to the bacteria culture in 38 cases. 13 cases were caused by gram-positive cocci, 13 cases were caused by gram-negative bacilli, 8 cases were caused by fungi and 4 cases were caused by gram-positive bacilli. Final visual acuity in 11 of 38 eyes achieved 5/100 or better, including 7 cases of gram-positive cocci (58.3%), 2 gram-negative bacilli (16.7%), 2 fungi cases (25%), but no case in gram-positive bacilli. Both were significant (p<0. 05). Conclusions: Infectious endophthalmitis is mainly caused by gram-positive cocci and gram-negative bacilli. Prognosis of the gram-positive cocci is better than that in gram-negative bacilli.