摘要
以免疫电子显微镜和免疫萤光技术测试Ｃ型逆转录酶病毒。测定了神经性疾患病人和正常人各４０例的病毒抗原。结果正常人全部阴性，而病人阳性率为２２．５０％，差异非常显著（Ｐ＜０．０１）；且在抗原阳性标本中见Ｃ型病毒颗粒。提示国内神经性疾病与Ｃ型逆转录病毒感染有关。另检测了５０例正常人和５４例神经性疾患病人血清病毒抗体，显示正常人全部阴性，病人阳性率为１．８５％，无显著差异（Ｐ＞０．０５）。但病人病毒抗原和抗体的阳性率相比，差异非常显著（Ｐ＜０．０１），说明测试抗原比抗体敏感。
Immunofluorescence and immunoelectronmicroscopy assay were used for detdction ofType-C retrovirus.We tested 104 samples in which 50 were obtained from healthy adultsand 54 from patients with neurogenic diseases。40 samples from patients were tested forretrovirus antigen and 9 found to be positive(22.5%).All normal samples were retrovirusantigen negative. The statistical difference in positive rate between the two groups is signifi-cant(P<0.01 ).The virus particles with type C morphology were observed in one positivesample.The results suggest that retrovirus may have relation to neurogenic diseases。In ad-dition,we tested 54 sera from the patients for retrovirus antibody and only one sample waspositive(1.85%).The positive rte of retrovirus antigen was much higher than that of anti-body in patients with neurogenic diseases(P<0.01).
出处
《江西医学院学报》
1994年第2期8-11,F003,共5页
Acta Academiae Medicinae Jiangxi
基金
江西省自然科学基金
