和胃清肠饮治疗晚期胃肠道肿瘤化疗所致的腹泻(肠道湿热证)24例

Therapeutic effect of Heweiqingchang decoction on 24 cases of diarrhea caused by chemotherapy

目的 观察和胃清肠饮对晚期胃肠道肿瘤化疗所致的肠道湿热型腹泻的疗效和全身证候改善情况。方法 4 4例随机分为治疗组 2 4例和对照组 2 0例。治疗组口服和胃清肠饮 ,每日 1剂 ,分早、晚 2次服 ;对照组口服培菲康胶囊 ,每日 3次 ,每次 2粒。 2组均以 5日为 1个疗程。观察患者腹泻和全身症状的变化。结果 治疗组治愈率为 83.3% ,总有效率为 10 0 .0 % ;对照组治愈率为 2 0 .0 % ,总有效率为 65 .0 % ,2组比较均有极显著性差异 (P <0 .0 1)。在全身证候改善方面 ,治疗组有效率也明显优于对照组 (P <0 .0 1)。结论 和胃清肠饮治疗化疗所致腹泻疗效确切 。

Objective To observe the therapeutic effect of Heweiqingchang decoction on diarrhea caused by chemotherapy in patients of advanced gastrointestinal tract tumor. Methods Forty four patients were randomly classified into two groups, in treatment group(n=24) Heweiqingchang decoction was orally taken,one dose daily,taken in two times(morning and evening);in control group (n=20) Bifico capsule was orally taken two pills each time, three times per day, with a therapeutic course of five days for both groups. Results The cure rate and total effective rate in treatment group were 83.3% , 100% respectively;as compared with 20.0%, 65.0% in control group, the differences between two groups were significant (P<0.01). The effective rate of improving symptoms in treatment group was significantly higher than that in control group(P<0.01).Conclusion Heweiqingchang decoction is effective for treating diarrhea caused by chemotherapy, and can improve the quality of life of patients with tumor. [