口腔颌面外科领域组织工程学研究进展

Advances of tissue engineering research in oral-maxillofacial surgical field

口腔颌面组织工程研究是人体组织工程学研究一个重要组成部分。口腔颅颌面部集中了皮肤、粘膜、肌肉、骨骼、神经、腺体、牙齿、关节等诸多组织和器官 ,具有很大组织工程学研究价值、制品需求潜力和广阔的临床应用前景。同时 ,口腔颌面各组织器官由于其结构和功能上的特殊性 ,具有突出的区别于机体其它部位的组织工程学研究特点。本文将从牙齿、牙周、种植牙、唾液腺、颞颌关节、腭裂修复、皮肤粘膜、口腔颌面骨组织工程。以及基因工程与组织技术的联合应用等方面介绍近几年来国际国内口腔颌面外科领域的组织工程学研究进展。

Tissue engineering efforts in dentistry and maxillofacial surgery are aimed at reconstruction and repair of oral maxillofacial tissue,for restoration of function,and for cosmetics.With the advances of both biomedical engineering science and dentistry,scientists,engineers and dentists are now working as a team to use biocompatible resorbable matrices and living cells or growth factors to fabricate scaffolds that,when delivered in vivo,can induce hard or soft tissue formation at a desired site,It has a potential,in the field of stamatology,to regenerate TMJ cartilage,alveolar bone,oral mucosa,maxillofacial skin,muscle,nerves,salivary glands,teeth and periodontium with the tissue engineering techniques.so the development of the tissue engineered cellular dental and maxillary implants has a bright future and will bring about a new era to the fields of oral maxillofacial surgery.The present article tried to introduce the Intermational and domestic advances of the Tissue Engineering research in the fields of dentistry and oral maxillofacial surgery.