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火焰原子吸收光谱法和络合滴定法测定果胶钙的含钙率 被引量：4

Determination of Calcium in Calcium Pectinate by Flame Atomic Absorption Spectrophotometry and Compleximetry
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摘要 目的 :测定果胶钙的含钙率。方法 :果胶钙经硝酸消化处理 ,钙离子转变为可溶性的硝酸钙 ,用火焰原子吸收光谱法和 EDTA-2 Na络合滴定法测定果胶钙的含钙率 ,并对两种方法的相关性进行了考察。结果 :两种测定方法回收率和精密度均较好 ,且相关性显著 ( r=0 .996 1 )。结论 AIM The purpose is to establish methods to determine the calcium in calcium pectinate (CaP). METHODS The organic structure of CaP was destroyed by nitric acid and the combined calcium was released as calcium nitrate. Then Flame Atomic Absorption Spectrophotometry (FAAS) and Compleximetry by EDTA were employed respectively to determine the calcium. RESULTS The two established methods to determine the calcium in CaP were feasible with good recovery and precision, and there was a good correlation between the results by the two methods. CONCLUSION Either of the methods can be employed to determine calcium in quality control of CaP.
作者 熊小兵 张钧寿 张岚 黄悦 曹亮
机构地区 中国药科大学药剂学教研室
出处 《中国药科大学学报》 CAS CSCD 北大核心 2001年第5期367-370,共4页 Journal of China Pharmaceutical University
基金 国家"九五"科技攻关项目 (项目编号 :96 -90 2 -0 2 -13)
关键词 果胶钙 络合滴定 含钙率 火焰原子吸收光谱法 测定 Calcium pectinate FAAS Compleximetry
分类号 R927.2 [医药卫生—药学]
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参考文献10

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同被引文献35

  • 1吴丹,钱文,杨钻芷.原子吸收分光光度法测定龙牡壮骨冲剂中钙的含量[J].中国药科大学学报,1995,26(3):165-166. 被引量：6
  • 2张亚军,郑杭生,徐莲英.果胶在细菌触发型结肠定位给药制剂中的应用[J].中国医药工业杂志,2007,38(7):533-536. 被引量：10
  • 3中国药典.二部.2005.附录22
  • 4Friend DR. New oral delivery systems for treatment of inflammatory bow- el disease[J]. Adv Drug Deliv Rev,2005,57(2) :247.
  • 5Th. F. Vandamme, A: Lenourry, C. Charrueau, et al. The use of poly- saccharides to target drugs to the colon [ J ]. Carbohydrate Polymers , 2002,48(3) :219.
  • 6Morris ER,Powell DA,Gildey MJ, et al. Conformations and in terae- tions of pect ins. | . Polymorphism between gel and solid states of calci- um polygalacturonate [ J ]. J Mol Biol , 1982,155,507.
  • 7David T horn , Gregon T, Grant , et al. Rees. Characterisation of cation binding and gelation of polyuronates by circular diehroism [ J]. Carbo- hydrate Research, 1982,100:29.
  • 8Gregor T , Grant , Edwin R, et al. Rees. Biological interactions between polysaechafides and devalent cations : The egg - box model [ J ]. FEBS Letters, 1973,32 : 195.
  • 9Sayeh F. Ahrabi, Grete Madsen. et al. Development of pectin matrix tab- lets for colonic delivery of model drug ropivacaine [ J ]. European Jour- nal of Pharmaceutical Sciences ,2000,10(1) :43.
  • 10Bourgeois S, Laham A, Besnard M, et o.1. In vitro and in vivo evaluation of pectin beads for the coton delivery of beta - lactamases [ J]. J Drug Target,2005,13 (5) :277.

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中国药科大学学报
2001年 第5期

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