复杂部分性癫痫与海马硬化

Complex Partial Epilepsy and Hippocampal Cirrhosis

目的 探讨复杂部分性癫痫与海马硬化的关系。方法 采用冠状切面 ,左右对称 ,平行于脑干长轴 ,由白质前联合位置测量了 32例复杂部分性癫痫病人头MRI海马区体积。结果 32例复杂部分性癫痫病人中 2 4例有海马萎缩 ,占 75% ,高于文献 70 % ;32例中 8例首次部分性癫痫发作 5例有海马萎缩 ;其余 2 4例多次反复部分性癫痫发作者中 19例海马萎缩 ,P >0 0 5。以意识障碍为主要表现的复杂部分性癫痫病人 2 0例中 14例海马萎缩 ;以精神障碍为表现的 12例病人中有 10例海马萎缩 ,P >0 0 5。结论 海马硬化与复杂部分性癫痫发作次数、发作形式无关。

Objective To discuss the relationship between complex partial epilepsy(CPE) and hippocampal cirrhosis(HC).Methods 32 cases of CPE patients were detected with MRI in volume of hippocampal area at anterior white commission paralleled with long axis of stem in symmetric and coronary section.Results 24 of 32 cases of CPE had hippocampal atrophy(HA)(75%)and were higher than 70% of reported.5 cases among 8 CPE on first onset had hippocampal atrophy.19 cases among 24 recurrent CPE had HP P>0 05.There was HP in 14/20 CPE patients with main manifestations of consciousness disorder and in 10/12 CPE cases of mental disorder P>0 05.Conclusion There might be no relationship between the HC and times and form of onset of CPE.