162例次腹膜透析相关性腹膜炎临床分析

Clinical analysis on 162 episodes of CAPD-related peritonitis

目的 探讨持续性不卧床腹膜透析 (CAPD)相关性腹膜炎发生的影响因素。方法 从患者性别、年龄、职业、受教育程度、基础疾病、致病菌种类以及透析连接系统类型 7个方面回顾性分析我科近 6年来收治的 162例次CAPD相关性腹膜炎。结果 腹膜炎的平均发生率 ,女性低于男性 ,但无统计学意义 (P =0 .5 3 3 ) ;≤ 3 5岁和大学以上文化患者明显低于其他年龄和文化层次患者(P <0 .0 1) ;双联系统显著低于其他连接系统 (P <0 .0 0 1) ;农民患者明显高于其他职业组患者 (P <0 .0 1) ;在各种基础疾病中的分布差异无显著性 (P >0 .0 5 ) ;结核杆菌和真菌感染率有上升趋势。结论 CAPD相关性腹膜炎的发生与患者年龄、性别、职业、受教育程度、致病菌种类以及透析连接系统类型等诸因素有关 ;与ESRD的基础疾病关系不明显。

Objective To investigate the factors effecting CAPD related peritonitis. Methods 162 episodes of CAPD related peritonitis in our center during the past 6 years were reviewed retrospectively, average incidence of CAPD peritonitis was calculated according to patient′s age, sex, profession, educational condition, primary disease, pathogen and type of connection device of dialysis respectively. Then the relaptionship between CAPD peritonitis and each factor mentioned above was evaluated. Results The average incidence of CAPD related peritonitis, was lower in female than in male, but there was no statistical significance( P =0.533). It was distinctly lower in patients aged ≤35 years old than >35 years old ( P <0.01) ;peasant was higher than other professions( P <0.01). Patients with higher education level (university) suffered less peritonitis than that with lower education level( P <0.01). An increasing tendency was found in the infection rate of tuberculous bacillus and fungus. Pair connection system was lower than any other connection system in the incidence of peritonitis( P <0.001). Conclusion Correlation exists between CAPD related peritonitis and each of the factors as follows: patient′s age, sex, profession, educational level, pathogen or type of connection device. However, the primary disease of ESRD (such as diabetes mellitus) is not related to episode rate of peritonitis significantly.