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中枢多巴胺转运蛋白显像剂^(99)Tc^mTRODAT-1 被引量:1

(99)~Tc^m TRODAT 1:the central dopamine transporter imaging agent
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摘要 99Tcm- TRODA T- 1是一种新型中枢多巴胺转运蛋白显像剂 ,其 SPECT显像在帕金森氏病的早期诊断中具有重要的临床价值。文章综述了近年来 99Tcm- TRODAT- 1的生化及其标记制备、动物实验、显像方案和临床前研究方面的进展 ,展示了 99Tcm- TRODAT- Tc m TRODAT 1 is a novel technetium 99m complex as a dopamine transporter imaging agent. The imaging of SPECT with it will have an important value in the early diagnosis of Parkinson's disease. This article reviews the progress of this promising agent.
作者 张海琴
出处 《国外医学(放射医学核医学分册)》 2001年第3期100-103,共4页 Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词 ^99TC^M-TRODAT-1 多巴胺转运蛋白 单光子断层显像 帕金森病 Tc m TRODAT 1 dopamine transporter SPECT Parkinson's disease
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参考文献10

  • 1Kushner SA,Mc Elgin WT,Kung MP,et al.Kineticm odeling of[99m Tc]TRODAT- 1:a dopam ine trans-porter imaging agent[].The Journal of Nuclear Medicine.1999
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