综合治疗与单纯药物治疗抑郁症对比研究

A Comparison of the Comprehensive Intervention and Medication of Treating Depression

目的 :了解综合治疗与单纯药物治疗对抑郁症的疗效。方法 :将 60例患者随机分为两组。治疗组采用药物与每周 2次的支持性治疗和或每 2周 1次的系统性家庭治疗相结合。对照组单用抗抑郁药治疗。入院前、入院后第 2周进行一次HAMD评分 ,观察 3个月 ,通过HAMD评分变化、药物剂量及有效住院时间进行分析比较。结果 :综合治疗组HAMD减分下降快 ,药物剂量小 ,有效住院时间短 ,与单纯药物治疗相比差异有显著性 (P <0 .0 5或P <0 .0 1)。结论 :对抑郁症进行综合治疗是一种更为有效的方法。

Objective:To investigate the efficacy of comprehensive intervention and medication in the treatment of depression.Methods:A total of 60 inpatients who met CCMD-2-R criteria for depression were randomly assigned to 2 groups, one treated with antidepressant and supportive therapy twice a week and cognitive therapy and system family therapy once every 2 weeks, the other only with antidepressant. Before and after hospitalization, the hamilton depression scale(HAMD) was used to evaluate the patients once every 2 weeks for 3 months. A comparison was made between the two groups in respect of their HAMD scores, medication doses and the length of stay in the hospital were. Results:The HAMD score of those treated with comprehensive intervention decreased quicker than the of those with antidepressant only. In addition, the medication dose was lower, the length of stay shorter in those with the comprehensive intervention. The difference between the two groups was statistically significant(P<0.05 or 0.01). Conclusion:The comprehensive intervention is an effective protocol for treating depression.