汕头市人淋巴细胞白血病、淋巴瘤病毒抗体的检测

Serological Survery of HTLV-Ⅰ Infection in Shantou

收集汕头市白血病患者及南澳岛健康人血清标本２１８份，用间接免疫荧光法检测ＨＴＬＶ─Ⅰ抗体，结果检测阳性３份，阳性率为１３７％，其中急性白血病阳性率为３．３３％（１／３０），淋巴瘤为１６．６％（１／６），健康人为０．６２％，阳性率虽低于日本（９～２６％）及加勒比海（３．７％）等流行区，但高于非流行区（０．０５～０．０８％）以及曾毅（０．０８％）报道，与福建省沿海地区（１％）相似。首次报道广东汕头沿海地区也有ＨＴＬＶ─Ⅰ病毒感染，也可能与Ｔ细胞白血病、淋巴瘤有关。

We first investigated the prevalence of human T-lymphotropic virus type Ⅰ(HTLV-Ⅰ) infection in Shantou,located in Southeastern China. Sera from healthy idividuals (n=162)and patients(n=56)with T cell leukemia were screened for antibody to HTLV-Ⅰ using an indirect immunofluorescent assay. Three of 218 sera were seropositive for HTLV-Ⅰ.Seropositivity was 1.38%, Antibody titers ranged from 1:160 to 1:320. In the 3cases,one was a healthy individual and two were patients with lymphoid leukemia and lymphoma.