摘要
宫内病毒感染尤其是巨细胞病毒(CMV)感染是致畸的重要原因之一,为了解我市畸形儿病毒感染的状况,探讨CMV在致畸上的作用及相关性,本室从汕头市各医院收集了24例畸形儿(无脑儿、脊柱裂、异位心、多发性畸形、巨大肝等),取母、婴配对标本(包括羊水、母血、宫颈分泌物、乳汁及畸形儿心血、咽拭子)共128份进行常规病毒分离、鉴定,并用ELISA法测定母、婴血清中抗CMV、IgG、IgM抗体。结果从24例畸形儿中分离到CMV1例,HSV-2型1例,检出CMV-IgM3例(其中1例为CMV分离阳性),病毒检测阳性率为16.67%(4/24),而CMV占病毒感染的3/4,初步结果提示本市畸形儿病毒感染因素不容忽视,而在病毒感染中以CMV为主要病原。
Vrius infection in Uterus is one of the most important factors that lead to deformation of infants. In order to know the state of virus infection in congenital malformation in Shantou City, 128 samples from 24 cases of various abnormal infants were collected for virus isolation and anti-CMV IgG and IgM detection. The results showed that out of 24 cases there were 1 case positive for CMV, 1 case positive for HSV-2 isolation, and 3 cases positive for anti-CMV-IgM(1 case was also positive for CMV isolation). The infection rate of virus is 16. 67%(4/24) and 3 out of 4 cases(3/4)were CMV infection. The results indicated that virus infection may be one of the important factors for deformation of infants and CMV is a major pathogen.
出处
《汕头大学医学院学报》
1994年第1期17-19,共3页
Journal of Shantou University Medical College