强直性脊柱炎伴肺间质病的早期诊断

Interstitial lung disease of ankylosing spondylitis

目的 为早期发现强直性脊柱炎 (A S)患者肺部异常 ,采用肺高分辨率 CT(HRCT)进行检查。方法36例初次确诊 AS患者均查了细胞沉降率 (ESR)、C反应蛋白 (CRP)、HL A- B2 7、全胸片、肺 HRCT、骶髂关节 CT,伴肺部异常者查了肺功能。结果 肺 HRCT示 19例 (5 3% )患肺间质病变 (IL D) ,而全胸片仅 2例 (6 % )示 IL D。 19例患 IL D者作肺功能测定 ,15例正常 ,4例异常。结论 肺 HRCT对 AS患者 IL

Objective This study was to early discover the abnormality of lung on high resolution CT (HRCT) in patients with ankylosing spondylitis (AS).Methods Thirty six initially diagnosed patients with AS,all received examinations of ESR,CRP,HLA B27,plain chest radiography,HRCT,and sacroiliac joint CT.The patients with pulmonary abnormality went on pulmonary function test.Results HRCT revealed ILD in 19 patients (53%),whereas plain chest radiography revealed ILD in 2 patients (6%).19 patients with ILD who had undergone pulmonary function tests showed normal in 15 and abnormal in 4.Conclusion HRCT is of importance to early diagnosis for ILD in AS patients.