原发性肾小球疾病一氧化氮含量变化及其作用

The Quantity Change and Action of Nitric Oxide in Primary Glomeruli Disease

为了研究原发性肾小球疾病血一氧化氮含量变化及其作用。我们测定了 70例各种原发性肾小球疾病血一氧化氮含量 ,包括 :慢性肾炎 2 0例 ,原发性肾病综合症 15例 ,急性肾炎 10例 ,尿毒症 2 5例 ,并和 10例健康者作比较。结果 :急性肾炎明显升高 (P<0 .0 5 ) ,而慢性肾炎 ,原发性肾病综合症及尿毒症均明显下降 (P<0 .0 1,0 .0 1及 0 .0 5 )。说明 :一氧化氮在原发性肾小球疾病中的含量有双向变化。提示 :一氧化氮对原发性肾小球疾病有双重作用。

To study the quantity change and action of NO in primary glomeruli disease,we tested the guantity of NO of 70 patients of all kinds of primary glomeruli disease,Including:chronic glomerulonephritis 20 patients,primary nephrosis syndrome 15 patients,Acut glomerulonephritis 10 patients and Uremia 25 patients.And then,10 heaith people to parallel result:The guantity of NO in creased in Acut glomerulonehritis( P <0.05)。but is decreased in chronic glomerulonephritis,primary nephrosis syndrome and uremia ( P <0.01,0.01,and 0.05).Showed:the quantity of NO change in two ways in primary glomeruli disease,sugested:NO had two sides action te primary glomoruli disease.