摘要
应用 ELSA 法检测了105例甲、乙型肝炎患者和20例健康献血员血清肿瘤坏死因子(TNF)含量,结果显示:乙肝慢性迁延型、急性、急性重症、甲型肝炎,乙肝慢性活动型,慢性重症组血清 TNF 水平依次升高,与对照组比较均有显著性差异(P<0.01),甲型肝炎组血清 TNF 含量仅次于慢活肝组(P>0.05)和慢重肝组(P<0.05)。慢活肝与慢重肝组无论并发原发性腹膜炎与否仍以慢重肝组血清 TNF 含量居高。提示肝炎患者血清 TNF 含量与病情,不同类型病毒感染及内毒素关系密切。
The level of tumor necrosis factor(TNF)in serum of 105 patients with hepatitis A or hepatitis B and 20 Cases of blood donors was tested by ELISA assay.The result showed that the level of TNF in serum was elevated in the order of chronic persistent hepatitis B.acute hepatitis B、acute hepatitis serious B、hepatitis A、Chronic Active hepatitis B、Chronic hep- atitis serious B,which were different as compared with that of control group(P<0.01).The level of TNF in hepatitis A group was lower than the chronic active hepatitis B(P<0.05) and chronic serious hepatitis B(P<0.05)only.Compared with chronic active hepatitis B, whether complicated or no primary peritonilis,the level of TNF in serum of chronic hepatitis group was higher than that in chronic active hepatitis B.Above showed that the relationship between the level of TNF in Serum of hepatitis patients and different types of virus and inter- nal toxemia were very closed.
出处
《江西医学院学报》
1998年第4期71-73,共3页
Acta Academiae Medicinae Jiangxi
