硫喷妥钠麻醉下肌肉松弛药对血流动力学的影响

EFFECTS OF MUSCLE RELAXANTS ON HEMODYNAMICS DURING THIOPENTAL ANESTHESIA

本文用无创性心阻抗血流图对比观察了在硫喷妥钠(sp)麻醉下管箭毒碱(Tub)、琥珀胆碱(Scc)和本可松(PC)对血流动力学的影响。结果表明,Tub0.3～0.4mg/kg与sp8mg/kg合用时血流动力的变化与单用sp相似;Scc1.5～2mg/kg静注后30～45s MAP、TPR显著增加,Tub能预防之;PC4mg静注可缓解SP的血压下降。

With impedance cardiography,the effects of tubocurarine(Tub),snccinylcholine(Scc)and pancuronium(PC)on the hemodynamics during thiopental(SP)anesthesia were studied compara- tively.It was shown that the hemodynamic changes after administration of Tub(0.3-0.4mg/ kg)and SP(8mg/kg)were similar to that of SP given alone.MAP and TPR increased sign- ificantly 30-45 seconds after Scc(1.5-2mg/kg)injected intravenously,which might be preve- nted by Tub.PC(4mg)might attenuate the reduction of blood pressure caused by injection of SP.